Mfg Part Number
Ab00431-1.4
Vector Labs Ab00431-1.4 Anti-Human Muscle Acetylcholine Receptor [mAb 192], Mouse IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
Human muscle AChR.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | mAb 192 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | AChR |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; WB; Blocking |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 10759865 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody binds to human muscle AChR with a Kd of 10 pM, to mouse muscle AChR with a Kd of 50 pM, and to rat muscle AChR with a Kd of 646 nM. |
| Application Notes: | This antibody binds to the human muscle Acetylcholine receptor, which is a ligand-gated ion channel, transducing an action potential into the muscle cells. The antibody binds to the main immunogenic region (MIR) and prevents ligand-binding. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |