Mfg Part Number
Ab00439-23.0
Vector Labs Ab00439-23.0 Anti-TrkA [MNAC13], Rabbit IgG, kappa (200 μg)
Quick Overview
Human TrkA ECD.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | MNAC13 |
| Synonyms: | Tropomyosin Receptor Kinase; NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA; neurotrophic receptor tyrosine kinase 1; High Affinity Nerve Growth Factor Receptor; Tyrosine Kinase Receptor A |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; SPR; Blocking; IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds to the extracellular domain of TrkA. It was shown not to cross react with TrkB . Moreover MNAC13 is specific to TrkA with negligible reactivity to TrkB and TrkC. |
| Application Notes: | This antibody binds to human TrkA, a receptor tyrosine kinase involved in the development and the maturation of the CNS and the PNS through regulation of proliferation, differentiation, and survival of the sympathetic and nervous neurons. It is a receptor for NGF and phosphorylates several downstream proteins regulating a variety of signalling cascades. This antibody neutralizes the NGF-TrkA interation. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |