Mfg Part Number
Ab00452-1.1
Vector Labs Ab00452-1.1 Anti-EGFR [S3 12D], Mouse IgG1, kappa (200 μg)
Quick Overview
Human EGFR.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | S3 12D |
| Synonyms: | Epidermal growth factor receptor; ERBB; ERBB1; HER1; mENA; PIG61; NISBD2 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; IHC; WB; ICC; IF |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 8149964 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv antibody fragment |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv antibody fragment format, for improved compatibility with existing reagents, assays and techniques. |
| Application Notes: | The antibody binds specifically to EGFR, a cell-surface receptor which is part of the ErbB family of receptors. The EGFR is a receptor tyrosine kinase, which, upon activation by its ligands, such as epidermal growth factor and transforming growth factor alpha, triggers signal transduction pathways that increase cell migration, adhesion and proliferation. Mutations that lead to the overexpression of EGFR are associated with the development of cancer. The S3 12D antibody is prepared from isolation of phage antibodies of the spleen library. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |