Mfg Part Number
Ab00464-1.1
Vector Labs Ab00464-1.1 Anti-PfRH5 [9AD4], Mouse IgG1, kappa (200 μg)
Quick Overview
Human adenovirus serotype 5 (AdHu5).
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 9AD4 |
| Synonyms: | P. falciparum RH5; Plasmodium falciparum Reticulocyte-binding Protein Homologue 5 |
| Amount: | 200 μg |
| Application Codes Clone: | Block; ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Rabbit IgG format, for improved compatibility with existing reagents, assays and techniques. |
| Application Notes: | The antibody binds specifically to PfRH5, a member of the RH family of proteins of the Plasmodium falciparum which interacts with the surface protein basigin (CD147) of erythrocytes. The interaction between the two proteins is necessary for the parasitic invasion of erythrocytes, known to give rise to the pathology of malaria. The antibody 9AD4 inhibits parasitic growth, possibly by blocking the interaction of PfRH5 and another protein, or by blocking the processing of the PfRH5 protein. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |