Mfg Part Number
Ab00473-10.7
Vector Labs Ab00473-10.7 Anti-Integrin α-M [107], Human F(ab)2, AbFab2™ His-Tagged, kappa (200 μg)
Quick Overview
Wild type (WT) recombinant CD11b.
$595.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 107 |
| Heavy Chain Modification: | AbFab2™ His-Tagged |
| Synonyms: | CD11b; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; leukocyte adhesion receptor MO1; Neutrophil adherence receptor; complement receptor 3 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds to the MIDAS face of the A domain from integrin CD11b. |
| Application Notes: | The antibody binds specifically to integrin α-M, a protein subunit of the α-M- β-2 molecule, which is expressed on the surface of leukocytes. Integrin α-M is involved in the adhesive interaction between molecules of the innate immune system, and plays a role in the uptake of complement-coated particles. The monoclonal antibody 107 has a blocking activity by binding to the metal-ion-dependent-adhesion site, favouring a low affinity conformation of the antigen. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |