Mfg Part Number
Ab00476-1.1
Vector Labs Ab00476-1.1 Anti-CD55 [LU30], Mouse IgG1, lambda (200 μg)
Quick Overview
Human CD55.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | LU30 |
| Synonyms: | DAF; Complement decay-accelerating factor |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; IHC; WB |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 10363997 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Human format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody binds to CD55 with a Kd of 13 nM. |
| Application Notes: | The antibody binds specifically to CD55, a glycophosphatidylinositol-anchored protein which acts together with CD46 and CD59 to protect cells from complement-mediated cell lysis. The antigen recognises C4b, C3 and C3b complement components, and, by blocking their catalytic activity, inhibits the formation of the membrane attack complex. CD55 is overexpressed in many tumour cell lines, thereby inhibiting complement-mediated cell lysis and increases tumour resistance to immune attacks. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |