Mfg Part Number
Ab00478-23.0

Vector Labs Ab00478-23.0 Anti-17ß estradiol [10G6D6], Rabbit IgG, lambda (200 μg)

Quick Overview
estradiol-6-ethyl methoxy carbonyl (EMC)–bovine serum albumin (BSA).
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Product Class:Purified
Clone ID:10G6D6
Synonyms:17-beta-estradiol; E2; ethynyl estradiol; oestradiol
Amount:200 μg
Application Codes Clone:ELISA; WB; IP; RIA
Shipping Temperature:Wet Ice
Origin Pub PMID:11812141
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG1
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:This antibody binds specifically to 17β estradiol, a mammalian estrogenic steroid hormone that is produced in the ovaries, placenta, and testis.
Application Notes:This antibody binds 17ß estradiol with a sensitivity of 33 ± 9 pg/ml. In women, 17β estradiol plays an important role in the development of secondary sexual characteristics and the maturation of long bones. It is also responsible for the activation of certain oncogenes and can be involved in the development of breast cancer and cancer of the uterine lining. Anti-estradiol antibodies can be useful in the detection of hormone concentrations in serum samples. This can be used therapeutically to monitor follicular maturation in cases of female infertility and estradiol-secreting tumors.
More Information
Brand Vector Labs
UNSPSC 12161500