Mfg Part Number
Ab00482-10.6
Vector Labs Ab00482-10.6 Anti-2,3-dinor-6-keto-prostaglandin F1α [mAb6kPGF], Human Fab fragment, His-Tagged, kappa (200 μg)
Quick Overview
Human 2,3-dinor-6-keto PGF1α.
$595.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | mAb6kPGF |
| Heavy Chain Modification: | His-Tagged |
| Synonyms: | 2,3-dinor-6-keto-prostaglandin F1-alpha |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; RIA |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 20079714 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody binds to to 2,3-Dinor-6-keto-prostaglandin F1α with an IC50 of 2.2 pmol and an affinity (Kd) of 2.22 nM. |
| Application Notes: | The antibody binds specifically to 2,3-Dinor-6-keto-prostaglandin F1α, a major urinary metabolite of PGI2 (prostacyclin). PG12 is a product of cyclooxygenase, and acts as a potent vasodilator and inhibitor of platelet aggregation. 2,3-Dinor-6-keto-prostaglandin F1α is a stable urinary metabolite of PGI2, and its levels in the urine can be measured using monoclonal antibodies in immunoassays, giving an indication of the levels of PGI2 produced in the body. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |