Mfg Part Number
Ab00496-10.7
Vector Labs Ab00496-10.7 Anti-Prion [3F4], Human F(ab)2, AbFab2™ His-Tagged, kappa (200 μg)
Quick Overview
Hamster 263K PrPs.
$595.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 3F4 |
| Heavy Chain Modification: | AbFab2™ His-Tagged |
| Synonyms: | Major prion protein; p27-30; CD30 antigen; prion protein PrP; prion-related protein |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; WB; IHC; IP |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Application Notes: | The antibody binds specifically to prion, a misfolded protein that has the ability to enter healthy organisms and cause other misfolding of other proteins into their prion form. This plays an essential role in the pathogenesis of certain neurodegenerative disorders such as Creutzfeldt-Jakob disease (CJD), Gerstmann-Staussler syndrome (GSS) and bovine spongiform encephalopathy (BSE). These disorders are characterised by an accumulation of prion proteins in the brain, which have a disrupted secondary structure. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |