Mfg Part Number
Ab00517-2.0
Vector Labs Ab00517-2.0 Anti-Vα TCR [34], Mouse IgG2a, kappa (200 μg)
Quick Overview
Purified recombinant soluble TCR from the T-cell hybridoma 85.33, corresponding to V alpha 11
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 34 |
| Synonyms: | TCR variable alpha chain; T-cell receptor variable alpha chain |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; FC; WB |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 8700165 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds to the T-cell receptor alpha chains. |
| Application Notes: | The antibody binds specifically to the recombinant and native variable domain of the α chain which comprises the T-cell receptor (TCR). The TCR is a disulfide-linked heterodimeric protein expressed on the surface of T-cells in complex with CD3 and ζ-chain molecules. The receptor functions in the recognition of MHC molecule and the subsequent activation of T-cells. The monoclonal antibody 34 recognises Vα regions of TCRs expressed in the 85.33 arthritogenic T-cell hybridoma and can be used to analyse TCR V gene expression and for immunotherapy in T cell mediated autoimmunity. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |