Mfg Part Number
Ab00521-10.0
Vector Labs Ab00521-10.0 Anti-Morphine [12D4], Human IgG1, lambda (200 μg)
Quick Overview
Morphine-6-hemisuccinate conjugated with BSA.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 12D4 |
| Synonyms: | Morphium; (5alpha,6alpha)-17-Methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; WB |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 2555519 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody binds to morphine with an affinity (Kd) of 46 nM. |
| Application Notes: | The antibody binds specifically to morphine, an alkaloid opiate drug derived from the opium poppy administered for the management of narcotic pain. Morphine exerts its effects by binding to μ opiate receptors in the central nervous system and gastrointestinal tract, leading to analgesia and sedation, thereby increasing the patient's tolerance to pain. The monoclonal antibody 12D4 recognises the N-methyl to N-allyl substitution in the conversion of morphine to nalorphine. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |