Mfg Part Number
Ab00524-10.6
Vector Labs Ab00524-10.6 Anti-Basigin [Ab-1], Human Fab fragment, His-Tagged, kappa (200 μg)
Quick Overview
Recombinant ectodomains of human basigin.
$595.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | Ab-1 |
| Heavy Chain Modification: | His-Tagged |
| Synonyms: | CD147; BSG; Cluster of differentiation 147; Extracellular matrix metalloproteinase inducer; EMMPRIN; 5F7; Collagenase stimulatory factor; Leukocyte activation antigen M6; Tumor cell-derived collagenase stimulatory factor; TCSF |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; Block |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody binds to basigin with an affinity (Kd) of 4 nM reported for the original antibody. |
| Application Notes: | The antibody binds specifically to basigin, a protein of the immunoglobulin superfamily which is expressed on the surface of erythrocyte and acts as a receptor for the human malaria parasite P. falciparum. The recombinant chimeric monoclonal antibody Ab-1 acts by blocking the interaction between basigin and PfRH5, a ligand necessary for the P. falciparum erythrocyte invasion, thereby inhibiting the development of malaria. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |