Mfg Part Number
Ab00526-10.0
Vector Labs Ab00526-10.0 Anti-17-Hydroxyprogesterone [101.B11.1], Human IgG1, kappa (200 μg)
Quick Overview
Mouse 17-OHP.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 101.B11.1 |
| Synonyms: | 17-OHP; 17alpha-hydroxyprogesterone |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; EIA |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 1922102 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody binds to 17-OHP with a Kd of 2.9 nM reported for the original antibody. |
| Application Notes: | The antibody binds specifically to 17-OHP, an endogenous progestogen which acts as a chemical intermediate in the synthesis of steroid hormones such as corticosteroids, androgens and estrogens. 17-OHP levels are extremely high in patients who suffer from congenital adrenal hyperplasia (CAH), a disorder of the adrenal glands caused by the deficiency of 21-hydroxylase which catalyses the production of cortisol. This results in the accumulation of the cortisol precursors, and in particular of 17-OHP. Monoclonal antibodies that bind specifically to 17-OHP can therefore be used to measure 17-OHP levels in the diagnosis of CAH. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |