Mfg Part Number
Ab00535-1.1
Vector Labs Ab00535-1.1 Anti-CD11a [hu1124 (Efalizumab)], Mouse IgG1, kappa (200 μg)
Quick Overview
Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | hu1124 (Efalizumab) |
| Synonyms: | LFA-1; integrin alpha L |
| Amount: | 200 μg |
| Application Codes Clone: | Block; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric murine antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | Binds to human LFA-1. |
| Application Notes: | Efalizumab binds to the LFA-1 alpha I domain blocking the ICAM-1 binding site via steric hindrance. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |