Mfg Part Number
Ab00535-10.6-BS

Vector Labs Ab00535-10.6-BS Anti-CD11a [hu1124 (Efalizumab)], Human Fab fragment, His-Tagged, kappa (1 mg)

Quick Overview
Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.
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Product Class:Purified
Clone ID:hu1124 (Efalizumab)
Heavy Chain Modification:His-Tagged
Synonyms:LFA-1; integrin alpha L
Amount:1 mg
Application Codes Clone:Block; FC
Shipping Temperature:Wet Ice
Buffer Composition:PBS only.
Original Format:IgG1
Storage Temperature:Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.
Specificity Statement:Binds to human LFA-1.
Application Notes:Efalizumab binds to the LFA-1 alpha I domain blocking the ICAM-1 binding site via steric hindrance.
More Information
Brand Vector Labs
UNSPSC 12161500