Mfg Part Number
Ab00539-10.3

Vector Labs Ab00539-10.3 Anti-CD6 [OX-126], Human IgG1, Fc Silent™, kappa (200 μg)

Quick Overview
This antibody was raised by immunizing BALB/c mice with a fusion protein consisting of human CD6 domain 3 and rat CD4 domains 3 and 4 (CD6d3CD4d3 + 4) (corrected, see: (Hassan et al., 2019; pmid: 30890626)).
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Product Class:Purified
Clone ID:OX-126
Heavy Chain Modification:Fc Silent™
Synonyms:TP120; OX126; MRC OX-126; MRC OX 126
Amount:200 μg
Application Codes Clone:FC
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG1
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:This antibody is specific for the domain 2 of human CD6. Binding depends on a SNP ( R, amino acid 225).
Application Notes:This antibody is noncompetitive with OX125 and does not block CD6/CD166 interactions (Santos et al., 2019; pmid: 31162836).
More Information
Brand Vector Labs
UNSPSC 12161500