Mfg Part Number
Ab00547-8.4
Vector Labs Ab00547-8.4 Anti-CD134 [OX-40], Rat IgG2b, Fc Silent™, kappa (200 μg)
Quick Overview
OX40 antibody was prepared by immunizing mice with phytohaemagglutinin-activated rat lymph node cells.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | OX-40 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | TNFRS4; Tumor necrosis factor receptor superfamily member 4; OX40 antigen; OX40L receptor; OX40; MRC OX40; MRC OX-40; OX-40 |
| Amount: | 200 μg |
| Application Codes Clone: | FC; functional; FACS; IHC-fr; IP |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | OX-40 antibody binds specifically to CD4+ T blasts. CD134 is a protein of the TNFR superfamily. It binds to OX40 ligand of both the monomeric and trimeric states which results in co-stimulated proliferation. |
| Application Notes: | OX-40 antibody results in Fc-dependent (i.e. not Fab or F(ab')2) stimulation of in vitro activated T cell proliferation, but is not mitogenic for resting cells. This antibody can also label CD4+ T blasts and can pull down CD134/CD134+ cells. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |