Mfg Part Number
Ab00563-8.1
Vector Labs Ab00563-8.1 Anti-CD62L [OX-85], Rat IgG2b, kappa (200 μg)
Quick Overview
This antibody was prepared by immunizing 8 –12-week-old BALB/c mice with purified rat CD62L-CD4
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | OX-85 |
| Synonyms: | L-selectin; LECAM-1; Ly-22; MEL-14; CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LAM-1; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; Lymph node homing receptor; Lymphocyte antigen 22; Lymphocyte surface MEL-14 antigen |
| Amount: | 200 μg |
| Application Codes Clone: | FC; ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rat antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | OX-12 binds to rat antibody kappa light chains - has preference for IgKa allotype. |
| Application Notes: | This antibody binds to CD62L expressed on rat lymphocytes, and has been used to show that recombinant soluble rat CD62L-CD4, to which it also binds, is likely to be correctly folded (Nicholson, 1998). This antibody also labels, and can therefore be used to fractionate, the subpopulation of rat CD4+CD8- thymocytes that expresess L-selectin (Seddon, 1996). Cells with this phenotype are able to protect rats from diabetes upon adoptive transfer, as well as providing B cells with help for secondary antibody responses and mediating local graft-versus-host reactions. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |