Mfg Part Number
Ab00564-6.1
Vector Labs Ab00564-6.1 Anti-OX40L [OX-89], Rat IgG1, kappa (200 μg)
Quick Overview
This antibody was prepared by immunizing PVG rats with a recombinant chimeric protein consisting of domains 3 and 4 of rat CD4 and the extracellular region of mouse CD134L.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | OX-89 |
| Synonyms: | CD252; Tumor necrosis factor ligand superfamily member 4; OX40 ligand; CD134 ligand; OX40R |
| Amount: | 200 μg |
| Application Codes Clone: | IHC-fr; FC; blocking |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for murine CD252 (the ligand for OX40), expression of which is restricted to activated B cells, dendritic cells, microglia and endothelial cells. |
| Application Notes: | This antibody binds mouse CD134L, and has been shown to bind activated B cells and DCs, as well as CD134L-transfected fibroblast cells, though not activated T cells, in labelling and immunohistochemical analysis (Malmström, 2001). In addition, this antibody is able to partially block the interaction between CD134 and CD134L. This blocking effect could be responsible for the ability of this antibody to prevent T cell accumulation in the intestine of T cell-restored SCID mice and inhibits the development of Th1-mediated colitis. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |