Mfg Part Number
Ab00593-202.1
Vector Labs Ab00593-202.1 Anti-CD11a/CD18 [YKIX490.6.4], Dog IgG4 (IgG-D), kappa (200 μg)
Quick Overview
This antibody was prepared by immunizing rats with canine thymocytes
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | YKIX490.6.4 |
| Synonyms: | αLβ2 integrin; integrin alpha-L; integrin beta-2; LeuCAM |
| Amount: | 200 μg |
| Application Codes Clone: | Blocking; IHC-fr; IHC-paraffin; IHC-resin; FC; IP |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | lgG2c |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric dog antibody was made using the variable domain sequences of the original Rat IgG2c format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody recognizes canine LFA-1, an integrin consisting of a 180kDa CD11a chain complexed with a 95kDa common beta chain, CD18. LFA-1 is expressed on T cells, B cells, macrophages and neutrophils. |
| Application Notes: | This antibody binds CD11a/18, and has been shown to block T cell proliferation, cytotoxic T lymphocyte (CTL) lysis, antibody dependent cell mediated cytotoxic (ADCC) lysis and homotypic cell adhesion (Cobbold, 1994). This antibody has been used in IF and IP analysis to identify and characterise the canine homologue of human CD11a/18. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |