Mfg Part Number
Ab00604-2.0
Vector Labs Ab00604-2.0 Anti-CD45RO [UCH-L1], Mouse IgG2a, kappa (200 μg)
Quick Overview
Cultured T cells from an IL-2-dependent T-cell line (CA1) prepared from human peripheral blood activated with influenza virus.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | UCH-L1 |
| Synonyms: | PTPRC; Protein tyrosine phosphatase; receptor type C; CD45 R; UCHL1; UCHL-1 |
| Amount: | 200 μg |
| Application Codes Clone: | FC; IHC; IP; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody binds human CD45RO. |
| Application Notes: | PTPRC (CD45) is a transmembrane tyrosine phosphatase that is present on all leukocytes. PTPRC regulates the threshold of T cell antigen receptor (TCR) signaling through dephosphorylation of protein tyrosine kinases (e.g. Lck and Fyn). CD45R and CD45RO are two of multiple PTPRC isoforms generated by alternative splicing. CD45R is found on B lymphocyte and T lymphocyte subsets. CD45RO is present on 50% of T cells, most granulocytes and monocytes and most mature T cell tumours. This antibody reacts with an epitope unique for CD45R0. It may identify abnormalities of functional T-cell subsets in immune disorders, be used in tumour diagnosis by FACS or immunohistology and has been very useful in studies of human T cell function and ontogeny. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |