Mfg Part Number
Ab00611-10.6
Vector Labs Ab00611-10.6 Anti-TACE [D1 (A12)], Human Fab fragment, His-Tagged, kappa (200 μg)
Quick Overview
Recombinant human ADAM17 (TACE) ectodomain tagged to biotin.
$595.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | D1 (A12) |
| Heavy Chain Modification: | His-Tagged |
| Synonyms: | ADAM17; tumor necrosis factor-α-converting enzyme; CD156b |
| Amount: | 200 μg |
| Application Codes Clone: | Block |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody binds human (not mouse) TACE catalytic and non-catalytic domains. |
| Application Notes: | TACE (CD156b) has proved capable of cleaving epidermal growth factor receptor (EGFR) ligands, extracellular Notch1, cell-surface receptors, and adhesion molecules. As proteolytic cleavage is an indispensable activation event for many of these substrates, TACE has emerged as an attractive therapeutic target for the treatment of cancer and rheumatoid arthritis. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |