Mfg Part Number
Ab00624-7.1
Vector Labs Ab00624-7.1 Anti-CD43 [L11], Rat IgG2a, kappa (200 μg)
Quick Overview
L11 antibody was prepared by immunizing rats with mouse CD43.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | L11 |
| Synonyms: | gpL115; leukosialin; sialophorin; L-11; Spn; Ly-48; Ly48; B-cell differentiation antigen LP-3; B-cell differentiation antigen LP3; Leukocyte sialoglycoprotein; CD-43 |
| Amount: | 200 μg |
| Application Codes Clone: | FC; IHC; block; immunotherapy |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | L11 antibody binds specifically to mouse CD43. CD43 plays a role in the physicochemical properties of the T-cell surface and in lectin binding. CD43 is a major cell-surface sialoglycoprotein - also found on neutrophils, bone marrow stem cells, B-lineage cells after activation of thymocytes and T lymphocytes but is not expressed on resting B lymphocytes. The protein presents carbohydrate ligands to selectins and Is a counter-receptor for SN/Siglec-1. During T-cell activation it is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response. |
| Application Notes: | L11 has been shown to prevent the deveopment of diabetes in mice and has also been used for FC, IHC and to block the migration of T cells from the bloodstream |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |