Mfg Part Number
Ab00629-23.0
Vector Labs Ab00629-23.0 Anti-CD44 [Hermes-3], Rabbit IgG, kappa (200 μg)
Quick Overview
This antibody was produced by immunizing BALB/c mice with purified Hermes-1 antigen from KCA, a human B lymphoblastoid line that binds preferentially to mucosal HEV.
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| Product Class: | Purified |
|---|---|
| Clone ID: | Hermes-3 |
| Synonyms: | CDw44; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; CD44/H-CAM antibody; Hermes 3 |
| Amount: | 200 μg |
| Application Codes Clone: | Blocking; western blot; IHC; IF; FC; ICC; ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for CD44 (gp90 epitope cluster III). Hermes-3 recognizes Hermes antigen homologues on monkey, goat, and sheep lymphocytes. |
| Application Notes: | This antibody has been used in IF, IHC (immunoperoxidase method), cross-blocking and WB studies to characterise the Hermes-defined antigens (Picker, 1989). This antibody is able to block lymphocyte binding to mucosal HEV, without affecting binding to HEV in peripheral lymph nodes and synovium (Jalkanen, 1987). H3-51 is cross-blocked by this antibody, indicating that the epitopes recognized by these two antibodies overlap (Picker, 1989). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |