Mfg Part Number
Ab00631-1.32
Vector Labs Ab00631-1.32 Anti-GITR [YGITR765], Mouse IgG1-D265A, Fc Silenced, kappa (100 μg)
Quick Overview
nB2/6TG cells transfected with mouse GITR injected into DA rats.
$692.90
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | YGITR765 |
| Heavy Chain Modification: | Fc Silenced |
| Synonyms: | CD357; Tumor necrosis factor receptor superfamily member 18; TNFRSF18; AITR; GITR-D; activation-inducible TNFR family receptor; AITR; glucocorticoid-induced tumor necrosis factor receptor |
| Amount: | 100 μg |
| Application Codes Clone: | FC; block |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds murine GITR. |
| Application Notes: | A chimeric version of this antibody featuring a human IgG1 Fc-portion engineered to lack the N-linked glycosylation site at amino acid 297 was shown to enhance humoral immune responses by blocking GITR signallin (Ponte 2010). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |