Mfg Part Number
Ab00631-23.0

Vector Labs Ab00631-23.0 Anti-GITR [YGITR765], Rabbit IgG, kappa (200 μg)

Quick Overview
nB2/6TG cells transfected with mouse GITR injected into DA rats.
$517.40
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Product Class:Purified
Clone ID:YGITR765
Synonyms:CD357; Tumor necrosis factor receptor superfamily member 18; TNFRSF18; AITR; GITR-D; activation-inducible TNFR family receptor; AITR; glucocorticoid-induced tumor necrosis factor receptor
Amount:200 μg
Application Codes Clone:FC; block
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG2b
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:This antibody binds murine GITR.
Application Notes:A chimeric version of this antibody featuring a human IgG1 Fc-portion engineered to lack the N-linked glycosylation site at amino acid 297 was shown to enhance humoral immune responses by blocking GITR signallin (Ponte 2010).
More Information
Brand Vector Labs
UNSPSC 12161500