Mfg Part Number
Ab00687-1.1
Vector Labs Ab00687-1.1 Anti-E2 protein [Chk265], Mouse IgG1, lambda (200 μg)
Quick Overview
La Reunion 2006 OPY-1 strain of CHIKV injected into adult C57BL/6 mice deficient for interferon regulatory factor 7 with follow-up boosters.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | Chk265 |
| Synonyms: | CHIKV E2 B domain; B domain of the E2 glycoprotein |
| Amount: | 200 μg |
| Application Codes Clone: | NTRL; ELISA; crystallization; IF; FC; WB |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 26553503 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds to the B domain of the E2 glycoprotein of alphaviruses, such as Chikungunya virus, O’nyong’nyong virus, Ross River virus, Semliki Forest virus, Mayaro virus, Una virus, Getah virus, Bebaru virus, Middelburg virus, Barmah Forest virus. This antibody was successfully used to detect the E2 glycoprotein of La Reunion, Singapore, and LR2006_OPY1 CHIKV strains. |
| Application Notes: | This antibody binds to the B domain of the E2 glycoprotein of alphaviruses and protects against disease and virus dissemination in vivo (Pal et al., 2013; PMID: 23637602) (Fox et al., 2015; PMID: 26553503). The antibody detected CHIKV E2 secretion by AP-61 and C6/36 mosquito cell lines by western blot analysis (Tsai et al., 2023; PMID: 36434113). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |