Mfg Part Number
Ab00697-10.0
Vector Labs Ab00697-10.0 Anti-CD81 [1D6], Human IgG1, kappa (200 μg)
Quick Overview
This antibody was produced by immunizing mice with 5A6-aggregated OCI-LY8 B cells.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 1D6 |
| Synonyms: | Tetraspanin-28; TAPA-1; Target of the Antiproliferative Antibody 1; Tspan-28 |
| Amount: | 200 μg |
| Application Codes Clone: | Functional; ELISA; FC; ICC/IF; IHC-P; IP; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for human CD81, which is expressed on most tissues with the exception of red blood cells and platelets. |
| Application Notes: | This antibody is a strong inducer of homotypic adhesion in hematolymphoid cells (Levy, 1998). This antibody also has an anti-proliferative effect, and is able to induce growth inhibition of B cell lines. Triggering of CD81 by this antibody induces a significant upregulation of the constituitive release of TNF-α by JY cells, an Eptsein-Barr virus-positive B lymphoblastoid cell line (Altomonte, 1995). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |