Mfg Part Number
Ab00698-1.1
Vector Labs Ab00698-1.1 Anti-CD37 [MB-1], Mouse IgG1, kappa (200 μg)
Quick Overview
BALB/c mice were immunized with lymph node cells from a patient with nodular poorly differentiated lymphocytic lymphoma. Immunophenotyping studies of these cells identified them as B cells expressing SIgG/λ, as well as HLA-DR. Leu-12, and B1.
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| Product Class: | Purified |
|---|---|
| Clone ID: | MB-1 |
| Synonyms: | Tetraspanin-26; Tspan-26; Leukocyte antigen CD37; |
| Amount: | 200 μg |
| Application Codes Clone: | FC; ICC/IF; WB; IHC-P |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for human CD37, which is expressed on virtually all mature B lymphocytes, but not on pro-B or plasma cells. CD37 is highly expressed on all forms of B cell non-Hodgkin lymphoma, chronic lymphocyte leukemia, and other leukemias. CD37 does not appear to be expressed on T cells, thymocytes, granulocytes or platelets. |
| Application Notes: | This antibody recognizes human CD37, and has been used to identify and characterise the CD37 antigen in cell labelling, indirect immunofluorescence and IP analysis (Link, 1986). In particular, the use of this antibody to label malignant B cells indicates that expression of CD37 occurs relatively late in B cell maturation, as it is not expressed on "immature" B lineage lymphoid neoplasms. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |