Mfg Part Number
Ab00723-10.3
Vector Labs Ab00723-10.3 Anti-EGFR domain III [h-R3 (Nimotuzumab)], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody we generated by humanisation of the murine antibody R3, raised against EGFR purified from placenta membranes and A431 tumors.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | h-R3 (Nimotuzumab) |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | ERBB-D3; ERBB1; HER1; PIG61; mENA; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; epidermal growth factor |
| Amount: | 200 μg |
| Application Codes Clone: | block; FC; IHC |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 9154469 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | Binds to human EGFR domain III at a site distinct from antibody 7A7 (Ab00134) (Talavera et al. 2011) |
| Application Notes: | This antibody binds to human EGFR and inhibits EGF-dependent clonogenic growth of NRK cells and completely blocks EGF stimulated autophosphorylation of the receptor (Fernandez 1992) |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |