Mfg Part Number
Ab00732-23.0
Vector Labs Ab00732-23.0 Anti-HBeAg [E6], Rabbit IgG, kappa (200 μg)
Quick Overview
This antibody was produced by immunizing BALB/c and SJL/Olac mice with HBeAg derived by denaturing human liver HBcAg. The subsequent production of the Fab is not detailled.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | E6 |
| Synonyms: | HBV E-antigen; Hepatitis B Envelope Antigen |
| Amount: | 200 μg |
| Application Codes Clone: | Mab: RIA; cross-competition assay; serum protein electrophoresis. Fab; crystallization |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody defines the e-antigen determinant HBe-β, and is specific for unassembled dimers. Two copies of the antibody are able to bind captured HBeAg dimers, indicating two accessible epitopes per dimer. E6 binding is inhibited by other members of the e-β-reactive group of Mabs, namely e4, e8 and e9. |
| Application Notes: | This Fab forms a stable complex with the recombinantly-expressed HBeAg dimer. Consequently, this antibody can be used to facilitate the crystallization of the complex, and the establishment of its structure (DiMattia, 2013). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |