Mfg Part Number
Ab00749-1.1
Vector Labs Ab00749-1.1 Anti-RRV E2 [D7], Mouse IgG1, kappa (200 μg)
Quick Overview
This antibody was raised by immunizing mice.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | D7 |
| Synonyms: | RRV Envelope gp; Ross River Virus envelope glycoprotein; O’nyong-nyong VLP; Chikungunya VLP; CHIKV-VLP |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; FC; labelling |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for the E2 envelope protein of RRV. This antibody is also reported to cross react with O’nyong-nyong VLP and Chikungunya VLP (CHIKV-VLP). |
| Application Notes: | This antibody binds RRV E2, and has been used to stain RRV-positive cells and in FC analysis of E2 surface expression (Jupille, 2013). This antibody has also been used to detect RRV binding to HeLa cells, demonstrating that synthetic peptides representing the α1β1 integrin binding site on collagen IV are able to inhibit RRV binding to cells, thus implicating the α1β1 integrin as an RRV cell-binding receptor (La Linn, 2005). This antibody can be used for the detection of Ross river virus E2 protein, O’nyong-nyong VLP (ONNV VLP) and Chikungunya VLP (CHIKV-VLP) in an ELISA. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |