Mfg Part Number
Ab00766-3.3
Vector Labs Ab00766-3.3 Anti-Vaccinia A33 glycoprotein [A2C7], Mouse IgG2b, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was prepared by intranasally infecting BALB/c mice with an attenuated vaccinia virus (VACV) mutant, followed by a boost with an intravenous injection of UV-inactivated WT VACV.
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| Product Class: | Purified |
|---|---|
| Clone ID: | A2C7 |
| Heavy Chain Modification: | Fc Silent™ |
| Amount: | 200 μg |
| Application Codes Clone: | IF; neutralization |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for the VACV antigen A33, a viral glycoprotein associated with the outer membrane of extracellular enveloped viruses. A33 is known to elicit protective antibody responses. |
| Application Notes: | The specificity of this antibody for VACV has been confirmed by IF assays (Meng, 2011). This antibody exhibited strong complement-mediated neutralization of the extracellular enveloped form of vaccinia virus in the presence of complement, and was able to protect mice against weight loss and death following an in vivo VACV challenge (Matho, 2015). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |