Mfg Part Number
Ab00769-47.0
Vector Labs Ab00769-47.0 Anti-HBsAg [5C3], Human IgA2, kappa (50 μg)
Quick Overview
This antibody was prepared by immunizing BALB/c mice with a highly purified preparation of HBsAg.
$692.90
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| Product Class: | Purified |
|---|---|
| Clone ID: | 5C3 |
| Synonyms: | HBV surface antigen; Major surface protein |
| Amount: | 50 μg |
| Application Codes Clone: | RIA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for hepatitis B virus surface antigen, a common antigen on the surface of HBV-infected hepatocytes and the outer coat of the intact virus. It recognizes all known subtypes of HBsAg, and has a very high affinity constant for its HBsAg determinant. This antibody does not cross-react with 2C6 and 5D3, two other anti-HBsAg Mabs, as each recognizes a distinct and separate determinant on HBsAg. |
| Application Notes: | This antibody, when radio-labelled with iodine-125, has been used to develop highly sensitive solid-phase radioimmunoassays for the detection of HBsAg at subnanogram levels in human serum (Shafritz, 1982). Consequently, this antibody may be a useful reagent in the immunodiagnosis of hepatitis B infection. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |