Mfg Part Number
Ab00789-10.3
Vector Labs Ab00789-10.3 Anti-Glycophorin A M antigen [M2A1], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
M2A1 was prepared by immunzing BALB/c mice with human red blood cells of the M phenotype, and was screened by testing for anti-M activity.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | M2A1 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | CD235a; M sialoglycoprotein; PAS-2 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; immunoblot; inhibition assay |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | M2A1 binds specifically to the M antigen on human erythrocytes, and shows no reactivity to N antigen. The epitope for this antibody includes the amino-terminal serine residue and sialic acid residues of glycophorin A. The reactivity of M2A1 for M antigen is pH- and salt-dependent (optimum ~ pH8-9). Blood group antigen M is located on the major sialoglycoprotein (glycophorin A) of red blood cells. |
| Application Notes: | M2A1 can bind to M antigen of glycophorin A and can be used in ELISAs, immunoblots and modified M glycoprotein can be used for inhibition tests. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |