Mfg Part Number
Ab00797-23.0
Vector Labs Ab00797-23.0 Anti-desmosome/hemidesmosome [F12], Rabbit IgG, kappa (200 μg)
Quick Overview
F12 was established by fusing peripheral blood lymphocytes derived from a human vulgaris patient with a hetermyeloma cell line.
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| Product Class: | Purified |
|---|---|
| Clone ID: | F12 |
| Amount: | 200 μg |
| Application Codes Clone: | IF; IEM |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 9174592 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgM |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgM format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | F12 recognizes an unknown polypeptide of desmosomal and hemidesmosomal plaques with a MW of 185 kDa (determined from immunoblotting using bovine tongue epithelium extract as the substrate), and by IEM (immunoelectron microscopy) it was determined that it is the intracellular part of the desmosome that is bound (Gilbert, 1997). F12 shares some immunochemical properties with autoantibodies |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |