Mfg Part Number
Ab00810-10.3
Vector Labs Ab00810-10.3 Anti-E-protein DIII (C-C') [ZV-48], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was generated by infecting mice with 1000 FFU of ZIKV MR-766 followed by a booster at 30d post-infection of ZIKV H/PF/2013, respectively and given a final intravenous boost with live ZIKV DIII (amino acids 299 to 407 of the ZIKV E protein))
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| Product Class: | Purified |
|---|---|
| Clone ID: | ZV-48 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | ZIKV E; Envelope protein; ZV48 |
| Amount: | 200 μg |
| Application Codes Clone: | NTRL; crystallization; SPR; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2c |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2c format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | ZV-48 binds to the Zika virus envelope protein at domain III (DIII, C-C’ loop). No cross-reactivity with other tested flaviviruses has been reported. |
| Application Notes: | The original mouse IgG2c format has been shown to have neutralizing activity and has been used to label ZIKV infected cells (4% PFA fixation, 0.1% saponin permeabilization). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |