Mfg Part Number
Ab00813-1.68
Vector Labs Ab00813-1.68 Anti-PD-1 [RMP1-14], Mouse Bispecific, anti-mCD47, Bispecific antibody, kappa (50 μg)
Quick Overview
The original rat hybridoma was generated by immunizing Sprague Dawley rats with mouse PD-1-transfectked BHK cells. A P3U1 myeloma was used as the fusion partner.
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| Product Class: | Purified |
|---|---|
| Clone ID: | RMP1-14 |
| Heavy Chain Modification: | Bispecific antibody |
| Synonyms: | CD279; PD1; PDCD1; RMPI-14; RMP1/14; Programmed Death Receptor 1; Programmed Death 1 |
| Amount: | 50 μg |
| Application Codes Clone: | Block; FC; IHC-Fr |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This is a bispecific anti-mouse antibody created by fusing anti-CD47 VHH domains to the C-terminus of the heavy chains of the anti-mouse PD1 antibody clone RMP1-14 in a mouse IgG1 D265A format. The mouse IgG1 D265 a format is an Fc-silenced format, preven |
| Specificity Statement: | This antibody binds to murine PD-1. |
| Application Notes: | Binding of the original rat IgG2a antibody to PD1 has been reported to prevent binding of both B7-H1-Ig (PD-L1-Ig) and B7-DC-Ig (PD-L2-Ig) fusion proteins to PD1. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |