Mfg Part Number
Ab00830-1.1
Vector Labs Ab00830-1.1 Anti-CD8 [14], Mouse IgG1, kappa (200 μg)
Quick Overview
Murine antibodies were produced by immunising mice with human monocytes. Immunised cells were used to produce a hybridoma from which the antibodies were purified.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 14 |
| Synonyms: | Leu2; cluster of Differentiation 8; T lymphocyte differentiation antigen T8 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; FACS; IHC; IP; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | Clone 14 binds human CD8, which is a coreceptor for the T lymphocyte receptor (TCR). CD8 binds, as a heterodimer, to class 1 MHC molecules and facilitates antigen-specific activation of the adaptive immune response. CD8 mutations are associated with various immunodeficiencies and pathologies. |
| Application Notes: | Clone 14 has been used to investigate the cell type-dependent expression of CD8 in nephrectomised rats by IHC methods (Xiao et al, 2014), and can further be used for detection of T cell population subsets. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |