Mfg Part Number
Ab00847-10.3
Vector Labs Ab00847-10.3 Anti-Factor VII [RFF-VII/1], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was raised by immunising Balb/c mice with purified human factor VII.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | RFF-VII/1 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Coagulation factor VII; factor-VII; EC:3.4.21.21; Proconvertin; Serum prothrombin conversion accelerator; SPCA; Eptacog alfa |
| Amount: | 200 μg |
| Application Codes Clone: | Block; radioimmunoassay |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for human coagulation factor VII, a serine protease that initiates the extrinsic pathway of coagulation and circulates as a zymogen. |
| Application Notes: | This antibody binds with high affinity to human factor VII, and acts as an inhibitor of factor VII coagulation activity (Takase et al, 1988).When coupled to sepharose, this antibody has been used to deplete factor VII from plasma (Sarial et al, 2012). The specificity of this antibody for factor VII has been confirmed in a double monoclonal immunoradiometric assay for factor VII antigen (Takase et al, 1988). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |