Mfg Part Number
Ab00848-10.3
Vector Labs Ab00848-10.3 Anti-Factor VIII:c light chain [RFF-VIII:c/5], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was raised by immunising BALB/C mice with highly purified procoagulant factor VIII (VIII: C)
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | RFF-VIII:c/5 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | AHF; Antihemophilic factor; coagulation factor VIII; procoagulant component; coagulation factor VIIIc; DXS1253E; F8Ccoagulation factor VIII; factor VIII F8B; FVIII; HEMAF8B; Procoagulant component |
| Amount: | 200 μg |
| Application Codes Clone: | Block; column chromatography; immunoradiometric assay |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for a C-terminal site on human coagulation factor VIII, |
| Application Notes: | This antibody is a coagulation inhibitor, though displays only weak anticoagulant activity (Rotblat et al, 1983). It has been used as the solid-phase immunoadsorbent in a two-site immunoradiometric assay of Factor VIII:c (Rotblat et al, 1983).When bound to Sepharose columns, this antibody has been used to deplete factor VII:c from plasma through column chromatography (Takase et al, 1987). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |