Mfg Part Number
Ab00850-10.3
Vector Labs Ab00850-10.3 Anti-CD151 [11G5a], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
This antibody was raised by immunizing mice.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 11G5a |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Tetraspanin-24; GP27; MER2; Platelet-endothelial tetraspan antigen 3; PETA-3; RAPH; SFA1; TSPAN24; Cluster of Differentiation 151 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; FC; IHC; IP; IF; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds to the CD151-integrin α3β1 binding site of the CD151 extracellular domain. |
| Application Notes: | The antibody has been used in flow cytometry experiments and to assess the interaction of CD151 with integrins (Yauch 1998). CD151 can also regulate cell migration independent of integrins in cancer for tumour cell migration, and mAb 11G5a has been used for histologic detection of CD151 free in prostate cancer, which correlates with poor patient outcome (TD Palmer 2014). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |