Mfg Part Number
Ab00862-23.0

Vector Labs Ab00862-23.0 Anti-5-Hydroxymethylcytosine [AB3/63.3], Rabbit IgG, kappa (200 μg)

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5-Hydroxymethylcytosine conjugated to BSA.
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Product Class:Purified
Clone ID:AB3/63.3
Synonyms:5hmc; MABE176; 5hmeC; 5' hydroxymethyl; cytosine; 5'OH methyl cytosine; 5'OHmeC; 5hmc; 5-hmC
Amount:200 μg
Application Codes Clone:IF; Dot; IP
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG2a
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:The anti-5-Hydroxymethylcytosine antibody, clone AB3/63.3, detects 5-hydroxymethyl cytosine (hmc, 5hmc), but not 5-methylcytosine or unmethylated cytosine.
Application Notes:This antibody can be used to detect 5hmC by immunofluorescence and dot blot. Zhang et al. (2014, PMID: 24427299) used the original rat IgG2a format (under the name MABE176) in an immunoprecipitation experiment.
More Information
Brand Vector Labs
UNSPSC 12161500