Mfg Part Number
Ab00871-3.0
Vector Labs Ab00871-3.0 Anti-p63 [BU5], Mouse IgG2b, kappa (200 μg)
Quick Overview
This antibody was raised by immunising mice with cells of the human myeloma cell line RPMI-8226. Spleen cells from immunised mice were fused to cells of a BALB/c plasmacytoma cell line.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | BU5 |
| Synonyms: | Tumor protein 63; Chronic ulcerative stomatitis protein; CUSP; Keratinocyte transcription factor; KET; Transformation-related protein 63; TP63; Tumor protein p73-like; p73L; p40; p51 |
| Amount: | 200 μg |
| Application Codes Clone: | FC; IF |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody is specific for human p63, a type II transmembrane protein identified in the rough endoplasmic reticulum. Surface expression of p63 is characteristic of differentiated plasma cells, due to their high secretory activity. As a result, p63 acts as a plasma cell marker. It also plays an important role in the development of epithelial tissues. |
| Application Notes: | This antibody has been used to detect cells expressing p63, which is characteristic of B cells, in flow cytometric analysis of B cell surface antigen expression (Exley et al, 1987), and, similarly, to assess the extent of differentiation of Daudi cells towards the plasma cell phenotype by flow cytometry (Clemens et al, 1988). In immunofluorescence assays, this antibody strongly stains plasma cells in acetone-fixed human tonsil sections, particularly in inter-follicular T-dependent areas, in and around germinal centres and in subepithelial areas (Johnson et al, 1985). This antibody also strongly stains acinar epithelial cells in thyroid sections. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |