Mfg Part Number
Ab00882-1.32
Vector Labs Ab00882-1.32 Anti-ICOSL [HK5.3], Mouse IgG1-D265A, Fc Silenced, kappa (100 μg)
Quick Overview
This antibody was raised by immunizing SD rat with mouse B7h-transfected L cells and fusing immune splenocytes with P3U1 myeloma cells and screened for binding to mouse B7h-transfected NRK cells.
$692.90
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| Product Class: | Purified |
|---|---|
| Clone ID: | HK5.3 |
| Heavy Chain Modification: | Fc Silenced |
| Synonyms: | B7RP-1; B7-related protein 1; ICOS ligand; CD275; LICOS; B7h |
| Amount: | 100 μg |
| Application Codes Clone: | FC; Block |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody specifically binds to mouse ICOSL and competes with binding of ICOS. |
| Application Notes: | This antibody has been used to detect murine ICOSL by flow cytometry. It is able to block ICOSL interacting with ICOSL and inhibit T-cell proliferation in a collagen type II (CII)-induced arthritis model. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |