Mfg Part Number
Ab00884-1.32-BS
Vector Labs Ab00884-1.32-BS Anti-B7-H3 [MJ18], Mouse IgG1-D265A, Fc Silenced, kappa (1 mg)
Quick Overview
This antibody was generated by immunizing Sprague Dawley rats with B7-H3-Ig, consisting of the extracellular domain (aa1–242 of mouse B7-H3) linked to the Fc portion of mouse IgG2a, emulsified in CFA (Difco). The antibody was selected by its reactivity to mouse B7-H3-transfected cells, but not to parental cells by flow cytometry.
$5,162.30
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| Product Class: | Purified |
|---|---|
| Clone ID: | MJ18 |
| Heavy Chain Modification: | Fc Silenced |
| Synonyms: | CD276; B7H3 |
| Amount: | 1 mg |
| Application Codes Clone: | FC; Block |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS only. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody binds to mouse B7-H3 and does not react with other B7-family molecules. |
| Application Notes: | This antibody has been used to detect murine B7-H3 by flow cytometry. It blocks B7-H3 signalling and can supress priming of Th2-responses and thereby the development of asthmatic responses in an ovalbumin-induced asthma model in BALB/c mice. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |