Mfg Part Number
Ab00887-1.1
Vector Labs Ab00887-1.1 Anti-alpha-V integrin [EM01309], Mouse IgG1, kappa (200 μg)
Quick Overview
This antibody was raised by immunising rabbits, isolating B cells from the immunised rabbits and fusing these with a rabbit plasmacytoma cell line (established by Spieker-Polet et al., 1995) to produce stable hybridomas
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| Product Class: | Purified |
|---|---|
| Clone ID: | EM01309 |
| Synonyms: | CD51; Vitronectin receptor subunit alpha; av |
| Amount: | 200 μg |
| Application Codes Clone: | IHC; WB; FC; ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Rabbit IgG format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This pan-αv antibody is specific for the extracellular domain (amino acids 31 - 992) of the αv chain in all αv-containing heterodimeric complexes. |
| Application Notes: | This pan-αv-specific antibody has been used to detect αv integrin chains using ELISA and on Western blots (Goodman et al, 2012), and to specifically stain αv integrins in FFPE/TMA material (Goodman et al, 2012; Silginer et al, 2016; Roth et al, 2013). Murine antibodies are typically unable to detect FFPE-embedded integrins. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |