Mfg Part Number
Ab00900-1.6-BS
Vector Labs Ab00900-1.6-BS Anti-NMDA Receptor [17], Mouse Fab fragment, His-Tagged, kappa (1 mg)
Quick Overview
Monoclonal antibodies that bind rat GluN2B ATD were obtained by immunizing mice with the purified intact GluN1-GluN2B NMDA receptors. IgGs were purified from hybridoma cell culture supernatant by Protein-A Sepharose. Fab fragments have been prepared by papain proteolysis followed by re-chromatographing onto Protein-A Sepharose to remove Fc.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 17 |
| Heavy Chain Modification: | His-Tagged |
| Synonyms: | NMDAR; NMDA-R; Glutamate receptor |
| Amount: | 1 mg |
| Application Codes Clone: | Crystallography |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS only. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | Reacts specifically with rat GluN2B ATD. |
| Application Notes: | This antibody has been used for the crystallisation of the NMDA receptor in the absence of an allosteric inhibitor at 2.9A (Tajima 2016). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |