Mfg Part Number
Ab00907-10.3
Vector Labs Ab00907-10.3 Anti-CD8 [G10-1], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
Human CD8.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | G10-1 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | cluster of differentiation 8; G10.1; Tp32 |
| Amount: | 200 μg |
| Application Codes Clone: | IF; IHC; IP; FC; immunotoxin |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 8929708 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for human CD8, and binds human CD8+ T cells. It also cross-reacts with non-human primate CD8, including that of Macaca nemestrina (Southern pig-tailed macaque). |
| Application Notes: | This antibody has been used to stain cells expressing CD8 by indirect immunofluorescence (Uckun et al, 1989) and in immunohistochemical analysis of aortic and iliac artery tissue from nonhuman primates (Masuda & Ross, 1989). It has also been employed in immunoprecipitation and gel electrophoresis experiments to investigate cell surface CD8 complexes (Ledbetter et al, 1985). A FITC-conjugated version of this antibody has been used to identify T cell populations in flow cytometry experiments (Chen et al, 2003). When conjugated to the ribosome-inhibitory protein ricin, this antibody acts as a potent CD8+ T cell-directed immunotoxin (Uckun et al, 1989). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |