Mfg Part Number
Ab00911-10.0
Vector Labs Ab00911-10.0 Anti-DCIR [9E8], Human IgG1, kappa (200 μg)
Quick Overview
This antibody was raised by immunising BALB/c mice with a dendritic cell immunoreceptor ectodomain-human Fc fusion protein.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 9E8 |
| Synonyms: | CD367; Clec4A; C-type lectin domain family 4 member A; LLIR; CLECSF6; C-type lectin DDB27; C-type lectin superfamily member 6; Dendritic cell immunoreceptor; Lectin-like immunoreceptor |
| Amount: | 200 μg |
| Application Codes Clone: | FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | This antibody is specific for human DCIR, which is expressed by monocytes, B cells, neutrophils, granulocytes and dendritic cells. |
| Application Notes: | This antibody has been used in flow cytometric analysis of DCIR expression by peripheral blood mononuclear cells (Klechevsky et al, 2010). A recombinant humanised form of this antibody fused to protein antigens is under investigation as an antigen-targeting vaccine (Flamar et al, 2012), and has been shown to trigger antigen-specific CD8+ T cell immunity. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |